Diabetes mellitus is a lifestyle disorder that is associated with various adverse health outcomes, including cardiovascular disease (CVD) and unhealthy sleep patterns. Epidemiologic studies and other research emphasize the association between both long and short sleep duration, CVD, and metabolic disease. Both short sleep and a sleep duration exceeding eight hours are pro-inflammatory; however, the markers of inflammation are nonspecific, as they do not reflect sleep duration or health outcome.
A recent study published in the journal BMC Medicine explores the serum protein profile associated with sleep duration to identify any correlation between new-onset coronary heart disease (CHD) and DM. Study: Very short sleep duration reveals a proteomic fingerprint that is selectively associated with incident diabetes mellitus but not with incident coronary heart disease: a cohort study. Image Credit: Sklo Studio / Shutterstock.
com The current study examines proteins that may be implicated in different sleep durations to generate proteomic scores that can predict the sleep duration category for each score and identify associations between these scores with incident DM (iDM) and CHD (iCHD). Over 3,300 participants between the ages of 46 and 68 years were included in the study, from whom a total of 78 plasma proteins were measured. Although none of the study participants had a history of DM or CHD, any individual who developed iDM or iCHD was identified.
Sleep duration data were used to.
